Nano-Pulse Stimulation Therapy (Patreon)
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Nano-Pulse Stimulation (NPS) therapy applies nanosecond pulsed electric fields to cells and tissues. It is a nonthermal modality that uses ultrashort pulses of electrical energy in the nanosecond domain. The cellular response to this therapy can be quite varied depending on the number of pulses applied and the total energy delivered.
NPS therapy has been found to clear seborrheic keratosis lesions with an 82% efficacy and sebaceous gland hyperplasia with a 99.5% efficacy. Pilot studies on warts indicated that 60% of the NPS-treated warts were completely cleared within 60 days. NPS therapy can be used to treat cellular lesions in the epidermis and dermis without affecting noncellular components such as collagen and fibrin.
When NPS therapy is applied to normal abdominal and facial skin that is scheduled for resection, histological analysis can be performed after resection to determine the effects of the NPS treatment on skin structures. Within 1 day, the epidermis exhibits signs of regulated cell death that include the lack of nuclear staining with standard hematoxylin and eosin exposure to thin sections of tissue. One week later, this dead epidermal layer peels off the skin as a crust or scab revealing a regenerated epidermis below. By using the appropriate NPS therapy, the epidermis is regenerated without scarring and any lesion residing in the epidermis can be readily removed.
Based on: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8370293/
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