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Hey guys, this is the first in the series (of probably 6 videos) where I start with Aspirin and and chemically convert it to Tylenol. 

Also, I think this video might be error free...but please let me know if you catch anything. I've been making loads of typos lately :(

Files

Aspirin to Acetaminophen - Part 1 of 6: Extracting Aspirin from Pills

UPDATE: In this video, I am showing you guys what the "proper" procedure would be, but it is by no means the fastest. If you want the fastest way, follow chemplayers method. I just prefer to not evaporate solvents, but that takes extra time. I would use a gravity filtration though in both cases though. It's just as fast and doesn't have as many problems as a vacuum one. Still do a recrystallization though. Without a recryst/hot filtration, the ASA is still pretty dirty. Hey guys, today we are starting on the journey from Aspirin to Tylenol. Tell me what you guys wanna see by voting here: http://www.strawpoll.me/11567284 ChemPlayer video: https://youtu.be/oztnjTukbpE My old aspirin extraction video: https://youtu.be/LvYetXXnTmI Nile talks about lab safety: https://youtu.be/ftACSEJ6DZA -------------------------------- Patreon: https://www.patreon.com/nilered Youtube Membership: https://www.youtube.com/c/nilered/join NileRed Merch Store (NileRed Pin & Keychain): https://store.dftba.com/collections/nilered NileRed Website (Glassware & Beaker Mugs): https://nile.red -------------------------------- Instagram: https://www.instagram.com/nile.red Twitter: https://twitter.com/NileRed2 Discord: https://discord.gg/3BT6UHf

Comments

jason black

To get 33% as your final yield, you're going to need about an 85% yield rate at each of the 7 steps. That seems... challenging. I'm going to guess a yield of about 1%, for which you only have to hit an average yield rate of about 50%. Shall we start a pool? :)

nilered

Haha 1℅?? You have such little faith :p

Anonymous

When grinding aspirin, why not invert the grinder and pour the powder into the lid. Much easier.

nilered

I think I put too much aspirin in. The lid holds less I think. I could be totally wrong though

Anonymous

Sounds like this'll be an interesting series. Not sure I'd be brave enough to declare the yield though! 20% final yield seems like it's feasible to me - Good Luck!

nilered

We shall see. At least you have some faith in me. The other prediction I got was 1℅ haha

Adam Rak

my guess is 15% for final yield, but for that you will need a decent yield at every step