How to Reduce Harmaline to Tetrahydroharmine (Make your own THH) (Patreon)

Vid Link   Before asking a question, please read the FAQ: https://www.patreon.com/posts/22774475

Details on harmala interactions (safety): http://ayahuascasafety.org/?page_id=13

Food interactions: https://tinyurl.com/y2qyxm9l

IF you want to skip most of the work you can simply buy a quality harmine/harmaline product then do the THH reduction as shown in this video, its a much faster and easier process if you do it that way, and the raw extract is not very expensive OR you can just buy the finished purified product with THH (if you can find it).  Harmalas are legal in the U.S.  I trust this seller, quality product at reasonable price: harmalas.com/store/p1/Harmala-HCl.html (Dosage Guidelines are at the  bottom of this page)

Timecodes

0:00 Intro

1:01 Why trade harmaline for THH?

2:50 Alkaloid analysis of numerous ayahuasca samples

5:42 The chemistry of harmaline reduction explained

6:26 Things you will need

8:19 REDUCTION BEGINS

8:43 How much vinegar?

9:42 How much zinc?

11:08 Hydrogen gas observed

11:34 First decant and filter

12:07 Post filter decant

12:34 Ammonia shake test

13:44 Alkaloid precipitation

18:01 Filtering out the alkaloids

19:05 Washing the alkaloids

19:54 Drying

20:55 Storage

21:17 Dosage Guidelines

22:18 Dangerous Interactions

23:03 Acknowledgements

Product links: [Note: If you use any of my Amazon links it supports the channel!  (“As an Amazon Associate I earn from qualifying purchases.”)]

UPDATE: Since I made this video I have found that using magnesium ribbon instead of the zinc dust powder is the best way to go, it is much cleaner and makes the reduction happen much faster (can finish in 15 minutes but I would let it stir for at least 30 minutes just to make sure its complete).  I recommend:  https://amzn.to/31Xx6at (instead of the previously recommended "Zinc Dust Powder, Ultra High Purity 5-8 Micron").

You can use less than half the magnesium vs. zinc since the molecular weight is lower.  The actual formula is: (g of harmaline you are reducing)/214.26 * 3 = (g of Mg) / 24.305     Multiplying by 3 above is just a general rule of thumb because you want to use an excess there to ensure a complete reduction. Say for example you had 3g of harmaline, that would mean you should use: 3*(24.305/214.26) * 3 = g of Mg Or 1g of Mg (but it won't hurt anything if you use more).

Ammonia: https://www.acehardware.com/departments/home-and-decor/cleaning-and-disinfectants/all-purpose-cleaners/10183

Stainless steel funnel with strainer: https://amzn.to/2VxCkVO

16oz wide mouth jars: https://amzn.to/2SDLz4Z

Digital pH meter: https://amzn.to/2G4ZYTX

Coffee filters: https://amzn.to/2GY7iTP

White Vinegar: https://amzn.to/2LQHfN9

Nitrile gloves: https://amzn.to/2Vwn77c

Irrigation Syringe: https://amzn.to/2RGfbS0

Glass Measuring Cup: https://amzn.to/2Fr1Iqr

Magnetic Stirrer: https://amzn.to/2CSWGS0

For proper and safe dosing:

Gem scale for small precise measurements: https://amzn.to/332gHRZ

Milligram measuring spoons: https://amzn.to/2Vul4ka

Citations & References:

TiKHAL on THH: https://erowid.org/library/books_online/tihkal/tihkal54.shtml

A harm-reduction approach to the isolation of harmine and its hydrogenated derivatives from Peganum Harmala seed in low-tech settings

Frederick A.P. Van Der Sypt, M.D.

https://zenodo.org/record/154442#.XDym489KjGI

“DaBuzz” written out version of the harmala extraction TEK, step by step guide with THH reduction:

https://docs.google.com/document/d/1Iy2-m6iveLPogf8r_HfVFCOAa2lmDX_4_HZeXeyDWb8/edit

Alternate simple way to build a magnetic stirrer if you don’t want to buy one:

https://youtu.be/XbvSdN70hb0

(Note: many scrap electronics have small fans in them that can be used, unused humidifiers and little desk fans can also be repurposed).

Artwork used with permission: "Serotonin Synapse" by Unholyjacknife

Various Alkaloid Profiles in Decoctions of Banisteriopsis Caapi (J C Callaway):

https://catbull.com/alamut/Bibliothek/various%20alkaloid%20profiles%20in%20aya%20decoction.pdf

(Also mentions 80 day stability of alkaloid profile at room temp)

Entheogen Review 1995 (where Callaway talks about THH): https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=314689#post314689

Phytomedicine. 1998 Apr;5(2):87-96. doi: 10.1016/S0944-7113(9Cool80003-2.

Effects of Ayahuasca on the human EEG.

Don NS1, McDonough BE, Moura G, Warren CA, Kawanishi K, Tomita H, Tachibana Y, Böhlke M, Farnsworth NR.

https://www.sciencedirect.com/science/article/pii/S0944711398800032

Endlessness’ NGO data on alkaloid analysis of ayahuasca samples:

https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=925429#post925429

Stability / Shelf life of THH, see Jees’ microscopy work and taste test after 2 years stored as freebase at room temp:

https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=929802#post929802

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Links to all of my TEKs, Videos, Trip music, and frequently asked questions with answers can be found here: https://www.patreon.com/posts/22774475 (everything is made available for FREE, I do not use pay walls, support the work only if you feel like you've benefited from it and you are able to do so).